diff --git a/assets/js/phoenix_live_view/hooks.js b/assets/js/phoenix_live_view/hooks.js
index 0eb0adb688..28d1986824 100644
--- a/assets/js/phoenix_live_view/hooks.js
+++ b/assets/js/phoenix_live_view/hooks.js
@@ -264,6 +264,15 @@ Hooks.InfiniteScroll = {
     }
   },
 
+  updated() {
+    // Check if the scroll container still exists
+    // https://github.com/phoenixframework/phoenix_live_view/issues/4169.
+    if (!this.scrollContainer.isConnected) {
+      this.destroyed();
+      this.mounted();
+    }
+  },
+
   destroyed() {
     if (this.scrollContainer) {
       this.scrollContainer.removeEventListener("scroll", this.onScroll);